The Medical University of South Carolina says that in 2024 it became the first hospital system to offer Stanford Neuromodulation Therapy (SAINT), an accelerated form of TMS that compresses treatment into days rather than weeks. MUSC reported roughly 80% remission by day five.
SAINT delivers 10 sessions per day over five days, using individualized, imaging-guided targeting and a high total pulse count. MUSC reported an average time to remission of about 2.6 days and overall remission of 80–90% in treatment-resistant depression, compared with roughly 62% complete remission for traditional TMS.
The rollout carries historical significance: MUSC's Dr. Mark George pioneered clinical TMS in the early 1990s, and SAINT developers Nolan Williams and Brandon Bentzley trained under George and Dr. Baron Short, who now directs MUSC's Brain Stimulation Service.
For patients, the accelerated course compresses months of daily visits into a single week — a major access improvement for those in crisis.
Source
Reporting based on coverage from Medical University of South Carolina. This article is editorial summary intended for general information; it is not medical advice.
